N-acetyllactosamine conjugated to gold nanoparticles inhibits enteropathogenic Escherichia coli colonization of the epithelium in human intestinal biopsy specimens.
نویسندگان
چکیده
We previously reported that the bundle-forming pilus-mediated localized adherence of enteropathogenic Escherichia coli to HEp-2, T84, and Caco-2 cells is inhibited by N-acetyllactosamine neoglycoconjugates. The results presented here extend this observation to the epithelium of biopsy specimens obtained from the human adult duodenum, terminal ileum, and colon.
منابع مشابه
Interactions of enteropathogenic Escherichia coli with pediatric and adult intestinal biopsy specimens during early adherence.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 74 9 شماره
صفحات -
تاریخ انتشار 2006